A lateral flow biosensor for detection of single nucleotide polymorphism by circular strand displacement reaction.
نویسندگان
چکیده
A lateral flow biosensor for detection of single nucleotide polymorphism based on circular strand displacement reaction (CSDPR) has been developed. Taking advantage of high fidelity of T4 DNA ligase, signal amplification by CSDPR, and the optical properties of gold nanoparticles, this assay has reached a detection limit of 0.01 fM.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 68 شماره
صفحات -
تاریخ انتشار 2012